Injectable treatment with Perovial for Peyronie

Peyronie’s disease is a condition that causes abnormal curvature of the penis, along with pain and difficulties in sexual function. In its acute phase, it can progress rapidly, making it necessary to have an appropriate treatment to control the progression.

At Andrology Valencia, we offer treatment with Perovial, an injectable medication approved by the European Medicines Agency (EMA), the first of its kind to treat this disease in its most active phase.

What is the Periovial treatment?

Perovial is an injectable medical device composed of hyaluronic acid, specifically formulated to treat the acute phase of Peyronie’s disease. This solution acts directly on the hardened tissue plaques in the penis, helping to reduce curvature, relieve pain, and restore elasticity.

Perovial is the first injectable device with the specific indication of “treatment of the acute/active phase,” approved by the European Medicines Agency.

EMA

The treatment administration is minimally invasive, performed through intralesional injections by a specialized urologist or andrologist, ensuring its effectiveness and safety.

The hyaluronic acid in Perovial has moisturizing, antioxidant, and antifibrotic properties, promoting tissue regeneration and reducing the rigidity of the affected area. Thanks to its localized action, a more precise and effective treatment is achieved without the need for immediate surgical interventions.

Advantages of Perovial treatment

Perovial treatment stands out compared to other available approaches for Peyronie’s disease:

1

Local and precise efficacy

By being injected directly into the affected area, it increases the concentration of hyaluronic acid in the fibrotic tissue.

2

Prevention of progression

Helps reduce progressive curvature and alleviate pain associated with the disease.

3

Minimally invasive treatment

Intralesional injections are quick, safe, and have mild, easily manageable side effects.

This treatment is especially recommended for patients who wish to slow the progression of the disease and improve their quality of life without resorting to more invasive procedures.

Who can benefit from Perovial treatment?

This treatment is intended for adult men with Peyronie’s disease in the acute phase, especially those who present:

Progressive curvature of the penis

Increasing deviation of the penis during erections due to tissue fibrosis.

Pain during erection

Discomfort or pain when achieving an erection, related to inflammation in the affected area.

Sexual function alteration

Difficulties in sexual activity, such as erection or penetration, due to curvature and pain.

Perovial treatment is an early option for patients looking to control the progression of the disease and improve their quality of life, avoiding or delaying the need for surgery.

Perovial application procedure

The treatment with Perovial consists of weekly intralesional injections, performed over a period of 10 to 12 weeks. The application is tailored to the location and size of the plaques, ensuring high effectiveness.

The administration should be carried out solely by a specialized urologist or andrologist. During the first few days after the application, it is recommended to avoid sexual activity to optimize the results.

Possible reactions to the treatment

Although Perovial is a safe treatment, mild side effects may occur due to the intralesional injection, such as:

Pain or sensitivity at the injection site: temporary discomfort in the injection area.

Redness, swelling, or mild bruising: common local reactions that disappear quickly. 

Localized inflammation of rare occurrence: mild and temporary inflammation in the treated area. 

These effects are usually temporary and disappear shortly after the application.

Need more information about the treatment with Perovial in Valencia?

If you think you might have Peyronie’s disease or want more details about the treatment with Perovial, at Andrología Valencia, we help you make an accurate diagnosis and offer a personalized treatment plan.

Only a specialized professional can determine if Perovial is the most suitable option for your case and provide you with the safest treatment.